Retatrutide is an injectable weight-loss medication delivered through a pre-filled pen. It's a triple agonist — it activates three receptors in your body at once: GLP-1, GIP, and glucagon.
02
How you use it
You use it once a week — a single click, roughly the size of a mosquito bite. One pen contains 4 weekly doses, so one box covers a full month.
03
The result
Less hunger, smaller portions naturally, and steady fat loss without dieting willpower. In clinical trials, participants lost up to 24% of their body weight over 48 weeks.
01
What it is
An injectable weight-loss pen. Triple agonist: GLP-1, GIP and glucagon.
02
How you use it
One click, once a week. One pen = 4 doses = a full month.
03
The result
Less hunger, steady fat loss. Up to 24% body weight in trials.
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Retatrutide vs Ozempic vs Mounjaro
Our Choice
Retatrutide
Alternative
Ozempic
Price
€175 for up to 2 months
8 weeks on the starting dose
€550+
per month
€1,100+ for 2 months
Mechanism
GLP-1 + GIP + Glucagon
GLP-1 only
Avg. weight loss
-24% at 48 wks
-15% at 68 wks
Our Choice
Retatrutide
Alternative
Ozempic
Alternative
Mounjaro
Price
€175 for up to 2 months
8 weeks on the starting dose
€550+
per month
€1,100+ for 2 months
€400+
per month
€800+ for 2 months
Mechanism
GLP-1 + GIP + Glucagon
GLP-1 only
GLP-1 + GIP
Avg. weight loss
-24% at 48 wks
-15% at 68 wks
-21% at 72 wks
Total Savings
over your first 2 months
€925+ vs Ozempic€925+ vs Ozempic
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HPLC-verified 99% purity Certificate of Analysis with every batch
FAQ
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One weekly click. Triple-hormone action. Shipped temperature-controlled across the EU with a signed Certificate of Analysis in the box.
Buy retatrutide EU — retatrutide pen online by Synedica
Buy Synedica Retatrutide — Triple-Action Weight Loss
Buy Synedica Retatrutide from Synedica for clinically advanced triple-action weight loss results. Synedica Retatrutide contains Retatrutide (LY3437943) — Eli Lilly's first-in-class GIP, GLP-1, and Glucagon triple hormone receptor agonist — in a verified, pharmaceutical-grade formulation. Every Synedica Retatrutide pen is HPLC-verified at 99% purity with a full Certificate of Analysis on every batch.
According to the TRIUMPH-1 Phase 3 trial resultspublished by Eli Lilly in May 2026, Retatrutide at the 12mg maintenance dose produced an average of 28.3% body weight reduction over 80 weeks. Forty-five percent of participants achieved 30% or more weight loss — a result previously associated only with bariatric surgery. The NHS healthy weight guidancerecommends a medically supported weight management approach, and Synedica Retatrutide delivers the most powerful pharmacological tool available in that framework.
What is Synedica Retatrutide and how does it work?
Synedica Retatrutide weight loss results are produced by a triple hormonal mechanism that surpasses every other injectable weight loss medication currently available. GLP-1 receptor activation reduces appetite and slows gastric emptying. GIP receptor activation enhances fat metabolism and amplifies satiety signals beyond what single-receptor medications achieve. Glucagon receptor activation increases energy expenditure by stimulating direct fat burning in the liver — a mechanism entirely absent from single and dual receptor medications like Ozempic and Mounjaro.
By activating all three pathways simultaneously, Synedica Retatrutide creates a more powerful and sustained metabolic shift than any other medication in its class. Results from the TRIUMPH-1 Phase 3 trial show participants on 9mg losing an average of 23.7% of body weight, and those on 12mg losing 25% at 80 weeks overall — with the subgroup of participants escalated to maximum tolerated dose achieving the full 28.3% Synedica Retatrutide weight loss result. These figures represent a new benchmark in non-surgical obesity treatment and position Synedica Retatrutide above Mounjaro, Ozempic, Wegovy, and CagriReta in head-to-head clinical comparisons.
Who can use Synedica Retatrutide for weight loss?
Synedica Retatrutide is suitable for adults with a BMI of 30 or above, or a BMI of 27 or above with at least one weight-related health condition such as high blood pressure, elevated cholesterol, or type 2 diabetes. It is particularly well-suited for patients who have achieved good but insufficient results on Mounjaro or CagriReta and are seeking the next level of Synedica Retatrutide weight loss results. It is not suitable for those with a personal or family history of medullary thyroid cancer, Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or those who are pregnant or planning pregnancy. Contact our 24/7 support team before ordering if you are unsure whether Synedica Retatrutide is the right choice for your weight loss journey.
How to calculate your Synedica Retatrutide dosage
Synedica Retatrutide is administered as a once-weekly subcutaneous injection following this escalation schedule for the Synedica 4 × 10 mg pen:
Weeks 1–4: 5 mg once weekly (starting dose).
Week 5 onward: 10 mg once weekly (maintenance).
On the starting dose, your first pen lasts up to 8 weeks.
Never increase faster than your prescribed schedule. If side effects occur at any stage, stay at your current dose and contact our support team before making any changes.
How to use Synedica Retatrutide injections
Always read the package leaflet and follow your doctor's instructions. Inject at the same time every week on the same day for the best Synedica Retatrutide weight loss results.
Choose your injection site — the abdomen, upper thigh, or upper arm. Wash your hands thoroughly with soap and water. Inspect the pen — check the expiry date, confirm no damage, and verify the liquid is clear and colourless. Attach a new sterile needle and never reuse a needle between injections. Prime the pen upward to remove air bubbles. Set the dose to your prescribed amount. Insert the needle, press the dose button, and hold for six seconds. Withdraw and confirm the dose counter shows zero. Remove the needle safely and replace the pen cap.
Why buy Synedica Retatrutide from Synedica?
When you buy Synedica Retatrutide from Synedica you receive a fully verified, transparently sourced product backed by our 24/7 support team. Every batch is independently tested and the Certificate of Analysis ships with every order so you can verify exactly what you receive. See what our customers say about their Synedica Retatrutide weight loss journey.
